Although hyperadrenocorticism is a relatively common disease in dogs, diagnosis can be challenging due to earlier recognition of affected dogs and lack of a single test with both high sensitivity and high specificity. This article summarises the clinical and clinicopathological features of this disease, as well as the tests used to confirm a diagnosis and to differentiate between pituitary- and adrenal-dependent causes. Practical methods of maximising the clinician's ability to confirm a diagnosis in suspect cases are highlighted.

Sarah Knight -

Carmel T Mooney -

Shiel Robert -